Magnesium deficiency and myocardial infarct size in the dog

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Myocardial Infarct Size and Location

Recent infarcts were compared with the anatomic boundaries of the involved vascular bed in human hearts to determine the amount and location of necrosis in relation to the myocardium at risk. The coronary arteries were injected with BaSo4 in 18 human hearts with 3-16-day-old infarcts. Thin (3-4-mm) slices were cut at 10-15-mm intervals, photographed, x-rayed and used for histologic analysis. In...

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Limitation of experimental myocardial infarct size by magnesium sulfate pre-treatment in dogs.

The present study was designed to evaluate the ability of magnesium sulfate (30 mg/kg, iv, 24 hr and 2 hr prior) to limit myocardial infarct size following permanent left coronary artery occlusion in adult mongrel dogs. Non-perfused myocardium which is the area at risk was visualised by injecting methylene blue intraatrially, 24 hr after coronary artery occlusion. The infarcted myocardium was v...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1985

ISSN: 0735-1097

DOI: 10.1016/s0735-1097(85)80048-6